![]() The term cytokine storm is often used interchangeably with CRS but, despite the fact that they have similar clinical phenotype, their characteristics are different. ![]() When occurring as a result of a medication, it is also known as an infusion reaction. CRS is also an adverse effect of some monoclonal antibody medications, as well as adoptive T-cell therapies. ![]() It refers to cytokine storm syndromes (CSS) and occurs when large numbers of white blood cells are activated and release inflammatory cytokines, which in turn activate yet more white blood cells. Infusion-related reaction (IRR), infusion reaction, cytokine storm Ĭytokine release syndrome ( CRS) is a form of systemic inflammatory response syndrome (SIRS) that can be triggered by a variety of factors such as infections and certain drugs. Medical condition Cytokine release syndrome
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